Please use this identifier to cite or link to this item: https://libjncir.jncasr.ac.in/xmlui/handle/10572/1452
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dc.contributor.advisorManjithaya, Ravi-
dc.contributor.authorSingh, Sunaina-
dc.date.accessioned2014-12-02T13:43:54Z-
dc.date.available2014-12-02T13:43:54Z-
dc.date.issued2013-12-02-
dc.date.issued2013-
dc.identifier.citationSingh, Sunaina. 2013, Screening and identification of genes involved in autophagy and autophagy related pathways in the yeast Saccharomyces cerevisiae, MS thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru-
dc.identifier.urihttps://libjncir.jncasr.ac.in/xmlui/10572/1452-
dc.descriptionOpen Accessen_US
dc.description.abstractMacroautophagy (herein autophagy) is a mechanism in which cells sequester a part of cytoplasm within a double membrane structure called autophagosome and deliver it to the vacuole for degradation. The degradation products, like amino acids and other basic building blocks, are recycled back to the cytoplasm and are used up by the cell [1]. The process of autophagy is highly conserved from yeast to humans. This process was first reported by Christian de Duve [2]. Much of the insights on autophagy in yeast came from the work of Ohsumi’s group when they observed vesicular structures of about 300- 900 nm within the vacuoles during nutrient deficient conditions [3]. Apart from being cells’ adaptive response to provide energy and nutrients during starvation, it is also an innate mechanism of cells to degrade damaged or superfluous organelles and invading pathogens. Autophagy also plays a wide variety of physiological and pathophysiological roles which include development, antiaging, tumor suppression and antigen presentation [4].-
dc.language.isoEnglishen_US
dc.publisherJawaharlal Nehru Centre for Advanced Scientific Research-
dc.rights© 2013 JNCASR-
dc.subjectYeast-
dc.subjectSaccharomyces cerevisiae-
dc.titleScreening and identification of genes involved in autophagy and autophagy related pathways in the yeast saccharomyces cerevisiaeen_US
dc.typeThesisen_US
dc.type.qualificationlevelMasters-
dc.type.qualificationnameMS-
dc.publisher.departmentMolecular Biology and Genetics Unit (MBGU)-
Appears in Collections:Student Theses (MBGU)

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