Design, synthesis and applications of small molecular probes in studying canonical and non-canonical DNA structures

Abstract

In summary, the fundamental and structural aspects of canonical and non-canonical DNA structures and objective of the work is presented in the introduction chapter. The second, third and fourth chapters describe the development of fluorescence probes for various in vitro and in vivo applications in living cells. The fifth and sixth chapters demonstrate the importance of small molecular templates to bring about structural transitions of single stranded DNA and creating novel DNA systems with functional properties.