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Browsing by Author "Agren, Hans"

Browsing by Author "Agren, Hans"

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  • A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid beta Aggregates 
    Rajasekhar, K.; Narayanaswamy, Nagarjun; Murugan, N. Arul; Kuang, Guanglin; Agren, Hans; Govindaraju, T. (Nature Publishing Group, 2016)
    A major challenge in the Alzheimer's disease (AD) is its timely diagnosis. Amyloid beta (A beta) aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here, we demonstrate hemicyanine-based ...
  • SERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery tool 
    Karthigeyan, Dhanasekaran; Siddhanta, Soumik; Kishore, Annavarapu Hari; Perumal, Sathya S. R. R.; Agren, Hans; Sudevan, Surabhi; Bhat, Akshay V.; Balasubramanyam, Karanam; Subbegowda, Rangappa Kanchugarakoppal; Kundu, Tapas Kumar; Narayana, Chandrabhas (National Academy of Sciences, 2014)
    We demonstrate the use of surface-enhanced Raman spectroscopy (SERS) as an excellent tool for identifying the binding site of small molecules on a therapeutically important protein. As an example, we show the specific ...

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