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Browsing by Author "Sadhale, Parag P"

Browsing by Author "Sadhale, Parag P"

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  • Polyisoprenylated Benzophenone, Garcinol, a Natural Histone Acetyltransferase Inhibitor, Represses Chromatin Transcription and Alters Global Gene Expression 
    Balasubramanyam, Karanam; Altaf, M; Varier, Radhika A; Swaminathan, V; Ravindran, Aarti; Sadhale, Parag P; Kundu, Tapas K (American Society for Biochemistry and Molecular Biology Inc, 2004-08-06)
    Histone acetylation is a diagnostic feature of transcriptionally active genes. The proper recruitment and function of histone acetyltransferases (HATs) and deacetylases (HDACs) are key regulatory steps for gene expression ...
  • Specific Inhibition of p300-HAT Alters Global Gene Expression and Represses HIV Replication 
    Mantelingu, K; Reddy, B A Ashok; Swaminathan, V; Hari Kishore, A; Siddappa, Nagadenahalli B; Pavan Kumar, G V; Nagashankar, G; Natesh, Nagashayana; Roy, Siddhartha; Sadhale, Parag P; Ranga, Udaykumar; Narayana, Chandrabhas; Kundu, Tapas K (Cell Press, 2007-06)
    Reversible acetylation of histone and nonhistone proteins plays pivotal role in cellular homeostasis. Dysfunction of histone acetyltransferases (HATs) leads to several diseases including cancer, neurodegenaration, asthma, ...
  • Transcriptional Coactivator PC4, a Chromatin-Associated Protein, Induces Chromatin Condensation 
    Das, Chandrima; Hizume, Kohji; Batta, Kiran; Kumar, B R Prashanth; Gadad, Shrikanth S; Ganguly, Semanti; Lorain, Stephanie; Verreault, Alain; Sadhale, Parag P; Takeyasu, Kunio; Kundu, Tapas K (American Society for Microbiology, 2006-11)
    Human transcriptional coactivator PC4 is a highly abundant multifunctional protein which plays diverse important roles in cellular processes, including transcription, replication, and repair. It is also a unique activator ...

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