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Revealing the trehalose mediated inhibition of protein aggregation through lysozyme-silver nanoparticle interaction
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| dc.contributor.author | Siddhanta, Soumik
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| dc.contributor.author | Barman, Ishan
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| dc.contributor.author | Narayana, Chandrabhas
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| dc.date.accessioned | 2016-10-18T04:48:45Z | |
| dc.date.available | 2016-10-18T04:48:45Z | |
| dc.date.issued | 2015 | |
| dc.identifier.citation | Soft Matter | en_US |
| dc.identifier.citation | 11 | en_US |
| dc.identifier.citation | 37 | en_US |
| dc.identifier.citation | Siddhanta, S.; Barman, I.; Narayana, C., Revealing the trehalose mediated inhibition of protein aggregation through lysozyme-silver nanoparticle interaction. Soft Matter 2015, 11 (37), 7241-7249. | en_US |
| dc.identifier.issn | 1744-683X | |
| dc.identifier.uri | https://libjncir.jncasr.ac.in/xmlui/10572/1878 | |
| dc.description | Restricted access | en_US |
| dc.description.abstract | We propose a facile and robust carbohydrate-mediated method for the prevention of nanoparticle induced denaturation and aggregation of proteins. Using label-free plasmon-enhanced Raman spectroscopy measurements, the mechanistic principles of trehalose stabilization in a model protein-nanoparticle system are elucidated for the first time, facilitating its further application in diagnostic and therapeutic nanoplex development. | en_US |
| dc.description.uri | 1744-6848 | en_US |
| dc.description.uri | http://dx.doi.org/10.1039/c5sm01896j | en_US |
| dc.language | English | en |
| dc.language.iso | English | en_US |
| dc.publisher | Royal Society of Chemistry | en_US |
| dc.rights | ?Royal Society of Chemistry, 2015 | en_US |
| dc.subject | Physical Chemistry | en_US |
| dc.subject | Materials Science | en_US |
| dc.subject | Physics | en_US |
| dc.subject | Polymer Science | en_US |
| dc.subject | Surface-Enhanced Raman | en_US |
| dc.subject | Circular-Dichroism Spectra | en_US |
| dc.subject | Bovine Serum-Albumin | en_US |
| dc.subject | Secondary Structure | en_US |
| dc.subject | Gold Nanoparticles | en_US |
| dc.subject | Conformational-Changes | en_US |
| dc.subject | Spectroscopy | en_US |
| dc.subject | Adsorption | en_US |
| dc.subject | Scattering | en_US |
| dc.subject | Stabilization | en_US |
| dc.title | Revealing the trehalose mediated inhibition of protein aggregation through lysozyme-silver nanoparticle interaction | en_US |
| dc.type | Article | en_US |
