DSpace Repository

Morphology and electrostatics play active role in neuronal differentiation processes on flexible conducting substrates

Show simple item record

dc.contributor.author Srivastava, Nishit
dc.contributor.author James, Jackson
dc.contributor.author Narayan, K. S.
dc.date.accessioned 2017-02-21T07:00:15Z
dc.date.available 2017-02-21T07:00:15Z
dc.date.issued 2014
dc.identifier.citation Srivastava, N; James, J; Narayan, KS, Morphology and electrostatics play active role in neuronal differentiation processes on flexible conducting substrates. Organogenesis 2014, 10 (1) 1-5, http://dx.doi.org/10.4161/org.27213 en_US
dc.identifier.citation Organogenesis en_US
dc.identifier.citation 10 en_US
dc.identifier.citation 1 en_US
dc.identifier.issn 1547-6278
dc.identifier.uri https://libjncir.jncasr.ac.in/xmlui/10572/2405
dc.description Restricted Access en_US
dc.description.abstract This commentary discusses and summarizes the key highlights of our recently reported work entitled "Neuronal Differentiation of Embryonic Stem Cell Derived Neuronal Progenitors Can Be Regulated by Stretchable Conducting Polymers." The prospect of controlling the mechanical-rigidity and the surface conductance properties offers a unique combination for tailoring the growth and differentiation of neuronal cells. We emphasize the utility of transparent elastomeric substrates with coatings of electrically conducting polymer to realize the desired substrate-characteristics for cellular development processes. Our study showed that neuronal differentiation from ES cells is highly influenced by the specific substrates on which they are growing. Thus, our results provide a better strategy for regulated neuronal differentiation by using such functional conducting surfaces. en_US
dc.description.uri 1555-8592 en_US
dc.description.uri http://dx.doi.org/10.4161/org.27213 en_US
dc.language.iso English en_US
dc.publisher Landes Bioscience en_US
dc.rights @Landes Bioscience, 2014 en_US
dc.subject Biochemistry & Molecular Biology en_US
dc.subject Developmental Biology en_US
dc.subject Engineering, Biomedical en_US
dc.subject Electrostatics en_US
dc.subject Cell Differentiation en_US
dc.subject Neuronal Cells en_US
dc.subject Stretched Substrates en_US
dc.subject Conducting Polymers en_US
dc.subject Polymer Poly(3,4-Ethylenedioxythiophene) Pedot en_US
dc.subject Stem-Cell Fate en_US
dc.subject Extracellular-Matrix en_US
dc.subject Neural Interfaces en_US
dc.subject Biomaterials en_US
dc.subject Adhesion en_US
dc.subject Microenvironments en_US
dc.subject Nanotopography en_US
dc.subject Proteins en_US
dc.title Morphology and electrostatics play active role in neuronal differentiation processes on flexible conducting substrates en_US
dc.type Editorial Material en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account