dc.contributor.advisor |
Ila, H. |
|
dc.contributor.author |
Acharya, Anand |
|
dc.date.accessioned |
2019-07-18T11:07:50Z |
|
dc.date.available |
2019-07-18T11:07:50Z |
|
dc.date.issued |
2018-01-29 |
|
dc.identifier.citation |
Acharya, Anand. 2018, New synthetic strategies for five membered heterocycles via novel organosulfur synthons, Ph.D thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru |
en_US |
dc.identifier.uri |
https://libjncir.jncasr.ac.in/xmlui/handle/10572/2640 |
|
dc.description.abstract |
For several years, our research group has been involved in design and
development of novel organosulfur building blocks and their synthetic applications for
construction of substituted and fused five/six membered heterocycles. In this chapter, a
brief account of these intermediates has been given.
1.1 Polarized Ketene Dithioacetals
The versatile synthon family of polarized ketene dithioacetals of the general
structure A has been proven to be among the simplest and useful synthetic building
blocks in various organic transformations.1 Among them, the corresponding α-oxoketene
dithioacetals have been extensively studied by our research group.1a-b
These organosulfur
synthons can easily be prepared by the reaction of CS2 with various active methylene
ketones in the presence of base followed by alkylation in one-pot reaction (Scheme 1). |
en_US |
dc.language.iso |
English |
en_US |
dc.publisher |
Jawaharlal Nehru Centre for Advanced Scientific Research |
en_US |
dc.rights |
© 2018 JNCASR |
|
dc.subject |
Heterocyclic compounds synthesis |
en_US |
dc.subject |
Organosulfur synthons |
en_US |
dc.title |
New synthetic strategies for five membered heterocycles via novel organosulfur synthons |
en_US |
dc.type |
Thesis |
en_US |
dc.type.qualificationlevel |
Doctoral |
en_US |
dc.type.qualificationname |
Ph.D. |
en_US |
dc.publisher.department |
New Chemistry Unit (NCU) |
en_US |