Evolutionary and Integrative Biology Unit (EIBU): Recent submissions

Now showing items 121-140 of 144

Probing The Circadian Oscillator Of A Mammal By Two-Pulse Perturbations

Sharma, Vijay Kumar; Chandrashekaran, M K (Marcel Dekker Inc, 2000)

When organisms are maintained under constant conditions of light and temperature, their endogenous circadian rhythms free run, manifesting their intrinsic period. The phases of these free-running rhythms can be shifted by ...
Circadian Dysfunction Reduces Lifespan In Drosophila Melanogaster

Kumar, Shailesh; Mohan, Ambika; Sharma, Vijay Kumar (Taylor & Francis Inc, 2005)

Circadian clocks regulate physiological and behavioral processes in a wide variety of organisms, and any malfunction in these clocks can cause significant health problems. In this paper, we report the results of our study ...
Effects of restricted feeding cycle on the locomotor activity rhythm in the mouse Mus booduga

Sharma, Vijay Kumar; Chidambaram, R; Subbaraj, R; Chandrashekaran, Maroli K (Pergamon-Elsevier Science Ltd, 2001-07-01)

The effect of restricted feeding (RF) cycles on the circadian locomotor activity rhythm was studied in the nocturnal field mouse Mus booduga. Mice were presented with a 2-h meal schedule every 24 h in continuous darkness ...
Zeitgebers (time cues) for biological clocks

Sharma, Vijay Kumar; Chandrashekaran, M K (Current Science Association, 2005-10-10)

The spatial and temporal aspects of the geophysical environment act as prominent selection forces for the evolution of life on this planet. The spatial features of the environment open up a choice of spatial niches and the ...
Does The Difference In The Timing Of Eclosion Of The Fruit Fly Drosophila Melanogaster Reflect Differences In The Circadian Organization?

Sheeba, V; Nihal, Manish; Mathew, S J; Swamy, Nagamani M; Chandrashekaran, M K; Joshi, Amitabh; Sharma, Vijay Kumar (Marcel Dekker, 2001)

The eclosion rhythm of a laboratory population of Drosophila melanogaster was studied under 12h light, 12h dark (LD 12:12) cycles. Although most of the flies were found to eclose just after "lights on" in LD 12:12, termed ...
PER/TIM-mediated amplification, gene dosage effects and temperature compensation in an interlocking-feedback loop model of the Drosophila circadian clock

Ruoff, Peter; Christensen, Melinda K; Sharma, Vijay Kumar (Academic Press Ltd Elsevier Science Ltd, 2005-11-07)

We have analysed a first-order kinetic representation of a interlocking-feedback loop model for the Drosophila circadian clock. In this model, the transcription factor Drosophila CLOCK (dCLK) which activates the clock genes ...
A case for multiple oscillators controlling different circadian rhythms in Drosophila melanogaster

Sheeba, V; Chandrashekaran, M K; Joshi, Amitabh; Sharma, Vijay Kumar (Elsevier Science Ltd, 2001-09)

A population of the fruit fly Drosophila melanogaster was raised in periodic light/dark (LD) cycles of 12:12 h for about 35 generations. Eclosion, locomotor activity, and oviposition were found to be rhythmic in these ...
Selection for early and late adult emergence alters the rate of pre-adult development in Drosophila melanogaster

Kumar, Shailesh; Vaze, Koustubh M; Kumar, Dhanya; Sharma, V K (BioMed Central Ltd, 2006-11-28)

Background: Circadian clocks have been implicated in the regulation of pre-adult development of fruit flies Drosophila melanogaster. It is believed that faster clocks speed up development and slower clocks slow it down. ...
A Simple Approach for the Computation of Multiple Periodicities in Biological Time Series

Rao, Anoop V; Sharma, Vijay Kumar (Swets & Zeitlinger, 2002-12)

We have described a simple approach for the analysis and isolation of multiple periodicities from a biological time series. For the estimation of the periodicities, we used simulated data and data from ongoing experiments ...
Intensity-Dependent Phase-Adjustments in the Locomotor Activity Rhythm of the Nocturnal Field Mouse Mus booduga

Sharma, Vijay Kumar; Chidambaram, R (Wiley-Liss, 2002-04-01)

The locomotor activity rhythm of the nocturnal field mouse Mus booduga was monitored under constant darkness (DD) and free-running periods (tau) were estimated. Following a free-run of about 15 days in DD, the animals were ...
Non-Ventral Lateral Neuron-Based, Non-PDF-Mediated Clocks Control Circadian Egg-Laying Rhythm in Drosophila melanogaster

Howlader, Gitanjali; Paranjpe, Dhanashree A; Sharma, Vijay Kumar (Sage Publications Inc, 2006-02)

The authors report the results of their study aimed at investigating the consequence of targeted ablation of ventral lateral neurons (LN(v)s-neurons regulating eclosion and locomotor activity rhythms) and genetic disruption ...
Circadian regulation of egg-laying behavior in fruit flies Drosophila melanogaster

Howlader, Gitanjali; Sharma, Vijay Kumar (Pergamon-Elsevier Science Ltd, 2006-08)

Significant progress has been made in our understanding of the neurogenetics of circadian clocks in fruit flies Drosophila melanogaster. Several pacemaker neurons and clock genes have now been identified and their roles ...
Chronobiotic effect of melatonin following phase shift of light/dark cycles in the field mouse Mus booduga

Singaravel, M; Sharma, V K; Subbaraj, R; Nair, Ν Gopukumar (Indian Academy Sciences, 1996-12)

The objective of this study was to assess whether melatonin accelerates the reentrainment of locomotor activity after 6 h of advance and delay phase shifts following exposure to LD 12:12 cycle (simulating jet-lag/shift ...
Possible evidence for morning and evening oscillators in Drosophila melanogaster populations selected for early and late adult emergence

Kumar, Shailesh; Kumar, Dhanya; Harish, V S; Divya, S; Sharma, Vijay Kumar (Pergamon-Elsevier Science Ltd, 2007-04)

In this paper, we report the results of our study aimed at a systematic analysis of the circadian phenotypes of fruit flies Drosophila melanogaster selected for early and late adult emergence, in light of the "morning and ...
Daylight and Artificial Light Phase Response Curves for the Circadian Rhythm in Locomotor Activity of the Field Mouse Mus booduga

Sharma, V K; Chandrashekaran, M K; Nongkynrih, P (Swets & Zeitlinger, 1997-08)

The sensitivity of the circadian pacemaker of the field mouse Mus booduga to diffuse daylight pulses of 15 min duration and 1000 lux intensity was measured in a series of experiments and a phase response curve (PRC) ...
Developmental plasticity of the locomotor activity rhythm of Drosophila melanogaster

Sheeba, V; Chandrashekaran, M K; Joshi, Amitabh; Sharma, Vijay Kumar (Pergamon Elsevier Science Ltd, 2002-01)

We used four replicate outbred populations of Drosophila melanogaster to investigate whether the light regimes experienced during the pre-adult (larval and pupal) and early adult stages influence the free-running period ...
Selection on the timing of adult emergence results in altered circadian clocks in fruit flies Drosophila melanogaster

Kumar, Shailesh; Kumar, Dhanya; Paranjpe, Dhanashree A; Akarsh, C R; Sharma, Vijay Kumar (Company Of Biologists Ltd, 2007-03-01)

To investigate whether circadian clocks in fruit flies Drosophila melanogaster evolve as a consequence of selection on the timing of adult emergence, we raised four replicate populations each of early (early(1..4)) and ...
The Drosophila Circadian Pacemaker Circuit: Pas de Deux or Tarantella?

Sheeba, Vasu; Kaneko, Maki; Sharma, Vijay Kumar; Holmes, Todd C (Taylor & Francis Inc, 2008)

Molecular genetic analysis of the fruit fly Drosophila melanogaster has revolutionized our understanding of the transcription/translation loop mechanisms underlying the circadian molecular oscillator. More recently, ...
A Simple Computer-aided Device for Monitoring Activity of Small Mammals and Insects

Sharma, Vijay Kumar (Swets & Zeitlinger, 2003)

A simple computer-aided device was developed to record the activity of small animals. The device comprises of aktographs, opto-couplers, opto-amplifier units, a data acquisition unit ('Activity Monitor') and a Pentium ...
Relationship Between Freerunning Period And Minimum Tolerable Light Pulse Interval Of Skeleton Photoperiods In Field Mice Mus Booduga

Sharma, Vijay Kumar; Singaravel, M; Chandrashekaran, M K; Subbaraj, R (Marcel Dekker Inc, 1997)

The entrainment of the circadian rhythm of locomotor activity was studied in the field mouse Mus booduga in order to examine the relationship between the free-running period (r) and minimum tolerable light pulse interval of ...

Now showing items 121-140 of 144

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