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Theoretical investigations of electronic structure and charge transfer properties of DNA and modified DNA

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dc.contributor.advisor Pati, Swapan K.
dc.contributor.author Mallajosyula, Sairam Swaroop
dc.date.accessioned 2012-09-12T09:24:18Z
dc.date.available 2012-09-12T09:24:18Z
dc.date.issued 2009
dc.identifier.citation Mallajosyula, Sairam Swaroop. 2009, Theoretical investigations of electronic structure and charge transfer properties of DNA and modified DNA, Ph.D thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru en_US
dc.identifier.uri https://libjncir.jncasr.ac.in/xmlui/handle/10572/826
dc.description.abstract Nucleic acids have been shown to be central molecules in transmission, expression, and conservation of genetic information. The classic experiments by Avery et al.[1] and Hershey et al.[2] demonstrated the role of deoxyribonucleic acid (DNA) as a carrier of genetic information. However, it was the elucidation of the DNA double helix structure by Watson and Crick[3], based on the X-ray fiber diffraction patterns generated by Franklin et al.[4] and Wilkins et al.[5], along with the chemical evidence of base complementarity proposed by Chargaff[6], that led to a molecular understanding of these key processes. The discovery of the structure of DNA and its relationship to key genetic processes had a tremendous impact on all subsequent biochemical investigations, defining the paradigm of modern biochemistry and molecular biology. It also established the primary importance of molecular structure for an understanding of the function of biological molecules and the need to investigate the relationship between structure and function.
dc.language.iso English en_US
dc.publisher Jawaharlal Nehru Centre for Advanced Scientific Research en_US
dc.rights © 2009 JNCASR en_US
dc.subject Electronic structure en_US
dc.subject Charge Transfer Properties of DNA en_US
dc.subject Modified DNA en_US
dc.title Theoretical investigations of electronic structure and charge transfer properties of DNA and modified DNA en_US
dc.type Thesis en_US
dc.type.qualificationlevel Doctoral en_US
dc.type.qualificationname Ph.D. en_US
dc.publisher.department Theoretical Sciences Unit (TSU) en_US


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