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Title: Identification of a Meiotic Prophase-specific Nuclear Matrix Protein in the Rat
Authors: Behal, Amita
Prakash, Kulkarni
Rao, M R S
Keywords: DNA binding
Meiotic Prophase-specific Nuclear Matrix Protein
Issue Date: 1987
Publisher: The American Society for Biochemistry and Molecular Biology Inc
Citation: Journal of Biological Chemistry 262(22), 10898-10902 (1987)
Abstract: We have identified a 110-kDa pI 5.6 phosphoprotein with DNA binding properties in the rat pachytene spermatocyte nuclear matrix. By immunoblotting and indirect immunofluorescence assays using polyclonal antibodies against the 110-kDa protein, we observed that it was germ cell nuclear matrix specific, more prominent in pachytene spermatocytes compared to premeiotic spermatogonia or postmeiotic round spermatids, and present in rat oocytes and in germ cells of mouse and monkey. We propose that this protein could play an important role in the meiotic process.
Description: Restricted access
Other Identifiers: 0021-9258
Appears in Collections:Research Papers (M.R.S. Rao)

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