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https://libjncir.jncasr.ac.in/xmlui/handle/123456789/3176| Title: | Role of lysine acetyltransferases p300/CBP in neurological disorders: implications in therapeutics |
| Authors: | Kundu, Tapas Kumar Singh, Akash Kumar |
| Keywords: | Neurological disorder Medicine |
| Issue Date: | 2017 |
| Publisher: | Jawaharlal Nehru Centre for Advanced Scientific Research |
| Citation: | Singh, Akash Kumar. 2017, Role of lysine acetyltransferases p300/CBP in neurological disorders: implications in therapeutics, MS thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru |
| Abstract: | 1. CSP-TTK21 could be delivered orally to the mice brain. 2. Oral delivery of CSP-TTK21 shows similar activity as IP administration. 3. CSP-TTK21 induces Long term potentiation (LTP) in hippocampal slices without altering the basal synaptic transmission. 4. CSP-TTK21 could rescue LTP deficits in Syngap1 heterozygous mouse model for Intellectual Disability (ID). |
| Description: | Open access |
| URI: | https://libjncir.jncasr.ac.in/xmlui/handle/123456789/3176 |
| Appears in Collections: | Student Theses (MBGU) |
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