Abstract:
1. CSP-TTK21 could be delivered orally to the mice brain.
2. Oral delivery of CSP-TTK21 shows similar activity as IP administration.
3. CSP-TTK21 induces Long term potentiation (LTP) in hippocampal slices without altering the
basal synaptic transmission.
4. CSP-TTK21 could rescue LTP deficits in Syngap1 heterozygous mouse model for Intellectual
Disability (ID).