Avinash, M. B.; Govindaraju, T.(Royal Society of Chemistry, 2014)
The stringent processes of natural selection and evolution have enabled extraordinary structure function properties of biomolecules. Specifically, the archetypal designs of biomolecules, such as amino acids, nucleobases, ...
Rajasekhar, Kolla; Narayanaswamy, Nagarjun; Mishra, Piyush; Suresh, S. N.; Manjithaya, Ravi; Govindaraju, T.(Wiley-V C H Verlag Gmbh, 2014)
Cyclic peptoids are potential candidates for diverse biological activities. However, applications of cyclic peptoids are limited by the synthetic difficulties, conformational flexibility of large cyclic peptoids, and lack ...
Pandeeswar, M.; Khare, Harshavardhan; Ramakumar, Suryanarayanarao; Govindaraju, T.(Royal Society of Chemistry, 2014)
The interfacing of aromatic molecules with biomolecules to design functional molecular materials is a promising area of research. Intermolecular interactions determine the performance of these materials and therefore, ...
Dwivedi, Atul K.; Pandeeswar, M.; Govindaraju, T.(American Chemical Society, 2014)
We report an amphiphilic perylene diimide (1), a bimolecular analog of L-3,4-dihydroxyphenylalanine (L-DOPA), as a reversible fluorescence switching probe for the detection and sensing of cationic surfactants and Fe3+/Cu2+ ...
A ratiometric, near-infrared (NIR), fluorescence and colorimetric probe DNPOCy for hydrogen sulfide (H2S) has been developed. The chemical basis for the operation of the probe is thiolysis of a dinitrophenyl ether, which ...
Sequence-specific recognition of DNA by small turn-on fluorescence probes is a promising tool for bioimaging, bioanalytical and biomedical applications. Here, the authors report a novel cell-permeable and red fluorescent ...
Pandeeswar, Makam; Senanayak, Satyaprasad P.; Narayan, K. S.; Govindaraju, T.(American Chemical Society, 2016)
The possibility of designing programmable thin-film supramolecular structures with spontaneous polarization widens the utility of facile supramolecular chemistry. Although a range of low molecular mass molecular single ...
Narayanaswamy, Nagarjun; Narra, Sivakrishna; Nair, Raji R.; Saini, Deepak Kumar; Kondaiah, Paturu; Govindaraju, T.(Royal Society of Chemistry, 2016)
Hydrogen peroxide (H2O2) is a key reactive oxygen species and a messenger in cellular signal transduction apart from playing a vital role in many biological processes in living organisms. In this article, we present phenyl ...
Avinash, M. B.; Swathi, K.; Narayan, K. S.; Govindaraju, T.(American Chemical Society, 2016)
We present a bioinspired design strategy to effectively tailor the assembly of naphthalenediimides (NDIs) into a wide variety of architectures by functionalizing with amino acid derivatives. This bioinspired process of ...
Pandeeswar, M.; Senanayak, Satyaprasad P.; Govindaraju, T.(American Chemical Society, 2016)
Reliable and ultrasensitive detection of mercury ions is of paramount importance for toxicology assessment, environmental protection, and human health. Herein, we present a novel optoelectronic approach based on nano ...
A major challenge in the Alzheimer's disease (AD) is its timely diagnosis. Amyloid beta (A beta) aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here, we demonstrate hemicyanine-based ...
Surface interactions at the biomaterial cellular interface determine the proliferation and differentiation of stem cells. Manipulating such interactions through the surface chemistry of scaffolds renders control over ...
Rajasekhar, K.; Madhu, Chilakapati; Govindaraju, T.(American Chemical Society, 2016)
Accumulation of amyloid beta (A beta) peptide and its aggregates in the human brain is considered as one of the hallmarks of Alzheimer's disease (AD). The polymorphic oligomers and fully grown fibrilar aggregates of A beta ...
Narayanaswamy, Nagarjun; Nair, Raji R.; Suseela, Y. V.; Saini, Deepak Kumar; Govindaraju, T.(Royal Society of Chemistry, 2016)
In this Communication, a molecular beacon-based DNA switch (LMB) is developed as an efficient and reversible pH sensing probe. Remarkably, LMB exhibited reversible structural transition between the closed (molecular beacon) ...
A simple solution-processing and self-assembly approach that exploits the synergistic interactions between multiple hydrogen bonded networks and aromatic interactions was utilized to synthesize molecular crystals of cyclic ...
Narayanaswamy, Nagarjun; Suresh, Gorle; Priyakumar, U. Deva; Govindaraju, T.(Royal Society of Chemistry, 2015)
Herein, the conventional and unconventional hydrogen bonding potential of adenine in APA for double zipper helical assembly of deoxyoligonucleotides is demonstrated under ambient conditions. The quantum mechanical calculations ...
A bioinspired nanoarchitectonics design strategy is adapted to construct 2D sheets of promising n-type organic semiconductor naphthalene diimide (NDI) with tunable size, shape and optoelectronic properties. Modulation of ...
Pandeeswar, M.; Khare, Harshavardhan; Ramakumar, Suryanarayanarao; Govindaraju, T.(Royal Society of Chemistry, 2015)
Crystallographic insight-guided nanoarchitectonics of peptide-conjugated naphthalene diimide (NDI) is described. In a bio-inspired approach, non-proteinogenic alpha-amino isobutyric acid (Aib)- and alanine (Ala)-derived ...
Rajasekhar, K.; Chakrabarti, Malabika; Govindaraju, T.(Royal Society of Chemistry, 2015)
Amyloidogenesis has been implicated in a broad spectrum of diseases in which amyloid protein is invariably misfolded and deposited in cells and organs. Alzheimer's disease is one of the most devastating ailments among ...