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Browsing Govindaraju, T. by Issue Date

Browsing Govindaraju, T. by Issue Date

Now showing items 1-19 of 19

A Thiazole Coumarin (TC) Turn-On Fluorescence Probe for AT-Base Pair Detection and Multipurpose Applications in Different Biological Systems

Narayanaswamy, Nagarjun; Kumar, Manoj; Das, Sadhan; Sharma, Rahul; Samanta, Pralok K.; Pati, Swapan Kumar; Dhar, Suman K.; Kundu, Tapas Kumar; Govindaraju, T. (Nature Publishing Group, 2014)

Sequence-specific recognition of DNA by small turn-on fluorescence probes is a promising tool for bioimaging, bioanalytical and biomedical applications. Here, the authors report a novel cell-permeable and red fluorescent ...
Nanoarchitectonics of biomolecular assemblies for functional applications

Avinash, M. B.; Govindaraju, T. (Royal Society of Chemistry, 2014)

The stringent processes of natural selection and evolution have enabled extraordinary structure function properties of biomolecules. Specifically, the archetypal designs of biomolecules, such as amino acids, nucleobases, ...
Biomimetic molecular organization of naphthalene diimide in the solid state: tunable (chiro-) optical, viscoelastic and nanoscale properties

Pandeeswar, M.; Khare, Harshavardhan; Ramakumar, Suryanarayanarao; Govindaraju, T. (Royal Society of Chemistry, 2014)

The interfacing of aromatic molecules with biomolecules to design functional molecular materials is a promising area of research. Intermolecular interactions determine the performance of these materials and therefore, ...
Assembly Modulation of PDI Derivative as a Supramolecular Fluorescence Switching Probe for Detection of Cationic Surfactant and Metal Ions in Aqueous Media

Dwivedi, Atul K.; Pandeeswar, M.; Govindaraju, T. (American Chemical Society, 2014)

We report an amphiphilic perylene diimide (1), a bimolecular analog of L-3,4-dihydroxyphenylalanine (L-DOPA), as a reversible fluorescence switching probe for the detection and sensing of cationic surfactants and Fe3+/Cu2+ ...
Synthesis of Hybrid Cyclic Peptoids and Identification of Autophagy Enhancer

Rajasekhar, Kolla; Narayanaswamy, Nagarjun; Mishra, Piyush; Suresh, S. N.; Manjithaya, Ravi; Govindaraju, T. (Wiley-V C H Verlag Gmbh, 2014)

Cyclic peptoids are potential candidates for diverse biological activities. However, applications of cyclic peptoids are limited by the synthetic difficulties, conformational flexibility of large cyclic peptoids, and lack ...
A probe for ratiometric near-infrared fluorescence and colorimetric hydrogen sulfide detection and imaging in live cells

Maity, Debabrata; Raj, Anand; Samanta, Pralok K.; Karthigeyan, D.; Kundu, Tapas Kumar; Pati, Swapan Kumar; Govindaraju, T. (Royal Society of Chemistry, 2014)

A ratiometric, near-infrared (NIR), fluorescence and colorimetric probe DNPOCy for hydrogen sulfide (H2S) has been developed. The chemical basis for the operation of the probe is thiolysis of a dinitrophenyl ether, which ...
Bioinspired Reductionistic Peptide Engineering for Exceptional Mechanical Properties

Avinash, M. B.; Raut, Devaraj; Mishra, Manish Kumar; Ramamurty, Upadrasta; Govindaraju, T. (Nature Publishing Group, 2015)

A simple solution-processing and self-assembly approach that exploits the synergistic interactions between multiple hydrogen bonded networks and aromatic interactions was utilized to synthesize molecular crystals of cyclic ...
Double zipper helical assembly of deoxyoligonucleotides: mutual templating and chiral imprinting to form hybrid DNA ensembles

Narayanaswamy, Nagarjun; Suresh, Gorle; Priyakumar, U. Deva; Govindaraju, T. (Royal Society of Chemistry, 2015)

Herein, the conventional and unconventional hydrogen bonding potential of adenine in APA for double zipper helical assembly of deoxyoligonucleotides is demonstrated under ambient conditions. The quantum mechanical calculations ...
Bioinspired Nanoarchitectonics of Naphthalene Diimide to Access 2D Sheets of Tunable Size, Shape, and Optoelectronic Properties

Pandeeswar, M.; Govindaraju, T. (Springer, 2015)

A bioinspired nanoarchitectonics design strategy is adapted to construct 2D sheets of promising n-type organic semiconductor naphthalene diimide (NDI) with tunable size, shape and optoelectronic properties. Modulation of ...
Crystallographic insight-guided nanoarchitectonics and conductivity modulation of an n-type organic semiconductor through peptide conjugation

Pandeeswar, M.; Khare, Harshavardhan; Ramakumar, Suryanarayanarao; Govindaraju, T. (Royal Society of Chemistry, 2015)

Crystallographic insight-guided nanoarchitectonics of peptide-conjugated naphthalene diimide (NDI) is described. In a bio-inspired approach, non-proteinogenic alpha-amino isobutyric acid (Aib)- and alanine (Ala)-derived ...
Function and toxicity of amyloid beta and recent therapeutic interventions targeting amyloid beta in Alzheimer's disease

Rajasekhar, K.; Chakrabarti, Malabika; Govindaraju, T. (Royal Society of Chemistry, 2015)

Amyloidogenesis has been implicated in a broad spectrum of diseases in which amyloid protein is invariably misfolded and deposited in cells and organs. Alzheimer's disease is one of the most devastating ailments among ...
Multi-Stimuli-Responsive Charge-Transfer Hydrogel for Room-Temperature Organic Ferroelectric Thin-Film Devices

Pandeeswar, Makam; Senanayak, Satyaprasad P.; Narayan, K. S.; Govindaraju, T. (American Chemical Society, 2016)

The possibility of designing programmable thin-film supramolecular structures with spontaneous polarization widens the utility of facile supramolecular chemistry. Although a range of low molecular mass molecular single ...
Nanoarchitectonics of Small Molecule and DNA for Ultrasensitive Detection of Mercury

Pandeeswar, M.; Senanayak, Satyaprasad P.; Govindaraju, T. (American Chemical Society, 2016)

Reliable and ultrasensitive detection of mercury ions is of paramount importance for toxicology assessment, environmental protection, and human health. Herein, we present a novel optoelectronic approach based on nano ...
Stimuli-responsive colorimetric and NIR fluorescence combination probe for selective reporting of cellular hydrogen peroxide

Narayanaswamy, Nagarjun; Narra, Sivakrishna; Nair, Raji R.; Saini, Deepak Kumar; Kondaiah, Paturu; Govindaraju, T. (Royal Society of Chemistry, 2016)

Hydrogen peroxide (H2O2) is a key reactive oxygen species and a messenger in cellular signal transduction apart from playing a vital role in many biological processes in living organisms. In this article, we present phenyl ...
A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid beta Aggregates

Rajasekhar, K.; Narayanaswamy, Nagarjun; Murugan, N. Arul; Kuang, Guanglin; Agren, Hans; Govindaraju, T. (Nature Publishing Group, 2016)

A major challenge in the Alzheimer's disease (AD) is its timely diagnosis. Amyloid beta (A beta) aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here, we demonstrate hemicyanine-based ...
Surface-Functionalized Silk Fibroin Films as a Platform To Guide Neuron-like Differentiation of Human Mesenchymal Stem Cells

Manchineella, Shivaprasad; Thrivikraman, Greeshma; Basu, Bikramjit; Govindaraju, T. (American Chemical Society, 2016)

Surface interactions at the biomaterial cellular interface determine the proliferation and differentiation of stem cells. Manipulating such interactions through the surface chemistry of scaffolds renders control over ...
Natural Tripeptide-Based Inhibitor of Multifaceted Amyloid beta Toxicity

Rajasekhar, K.; Madhu, Chilakapati; Govindaraju, T. (American Chemical Society, 2016)

Accumulation of amyloid beta (A beta) peptide and its aggregates in the human brain is considered as one of the hallmarks of Alzheimer's disease (AD). The polymorphic oligomers and fully grown fibrilar aggregates of A beta ...
A molecular beacon-based DNA switch for reversible pH sensing in vesicles and live cells

Narayanaswamy, Nagarjun; Nair, Raji R.; Suseela, Y. V.; Saini, Deepak Kumar; Govindaraju, T. (Royal Society of Chemistry, 2016)

In this Communication, a molecular beacon-based DNA switch (LMB) is developed as an efficient and reversible pH sensing probe. Remarkably, LMB exhibited reversible structural transition between the closed (molecular beacon) ...
Molecular Architectonics of Naphthalenediimides for Efficient Structure-Property Correlation

Avinash, M. B.; Swathi, K.; Narayan, K. S.; Govindaraju, T. (American Chemical Society, 2016)

We present a bioinspired design strategy to effectively tailor the assembly of naphthalenediimides (NDIs) into a wide variety of architectures by functionalizing with amino acid derivatives. This bioinspired process of ...

Now showing items 1-19 of 19

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