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Browsing Kavita Jain by Issue Date

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Now showing items 1-10 of 10

Purifying Selection, Drift, and Reversible Mutation with Arbitrarily High Mutation Rates

Charlesworth, Brian; Jain, Kavita (Genetics Society Americanica, 2014)

Some species exhibit very high levels of DNA sequence variability; there is also evidence for the existence of heritable epigenetic variants that experience state changes at a much higher rate than sequence variants. In ...
Two-point correlation function of an exclusion process with hole-dependent rates

Priyanka; Ayyer, Arvind; Jain, Kavita (American Physical Society, 2014)

We consider an exclusion process on a ring in which a particle hops to an empty neighboring site with a rate that depends on the number of vacancies n in front of it. In the steady state, using the well-known mapping of ...
Adaptive walks and distribution of beneficial fitness effects

Seetharaman, Sarada; Jain, Kavita (Wiley-Blackwell, 2014)

We study the adaptation dynamics of a maladapted asexual population on rugged fitness landscapes with many local fitness peaks. The distribution of beneficial fitness effects is assumed to belong to one of the three extreme ...
Length of adaptive walk on uncorrelated and correlated fitness landscapes

Seetharaman, Sarada; Jain, Kavita (American Physical Society, 2014)

We consider the adaptation dynamics of an asexual population that walks uphill on a rugged fitness landscape which is endowed with a large number of local fitness peaks. We work in a parameter regime where only those mutants ...
Effect of drift, selection and recombination on the equilibrium frequency of deleterious mutations

John, Sona; Jain, Kavita (Academic Press Ltd- Elsevier Science Ltd, 2015)

We study the stationary state of a population evolving under the action of random genetic drift, selection and recombination in which both deleterious and reverse beneficial mutations can occur. We find that the equilibrium ...
Response of Polygenic Traits Under Stabilizing Selection and Mutation When Loci Have Unequal Effects

Jain, Kavita; Stephan, Wolfgang (Genetics Society of America, 2015)

We consider an infinitely large population under stabilizing selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic ...
Real eigenvalues of non-Gaussian random matrices and their products

Hameed, Sajna; Jain, Kavita; Lakshminarayan, Arul (IOP Publishing Ltd, 2015)

We study the properties of the eigenvalues of real random matrices and their products. It is known that when the matrix elements are Gaussian-distributed independent random variables, the fraction of real eigenvalues tends ...
Deterministic evolution of an asexual population under the action of beneficial and deleterious mutations on additive fitness landscapes

Jain, Kavita; John, Sona (Academic Press Inc Elsevier Science, 2016)

We study a continuous time model for the frequency distribution of an infinitely large asexual population in which both beneficial and deleterious mutations occur and fitness is additive. When beneficial mutations are ...
Critical dynamics of the jamming transition in one-dimensional nonequilibrium lattice-gas models

Priyanka; Jain, Kavita (American Physical Society, 2016)

We consider several one-dimensional driven lattice-gas models that show a phase transition in the stationary state between a high-density fluid phase in which the typical length of a hole cluster is of order unity and a ...
Fixation probability of rare nonmutator and evolution of mutation rates

James, Ananthu; Jain, Kavita (Wiley-Blackwell, 2016)

Although mutations drive the evolutionary process, the rates at which the mutations occur are themselves subject to evolutionary forces. Our purpose here is to understand the role of selection and random genetic drift in ...

Now showing items 1-10 of 10

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