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Circadian disturbances are early features of neurodegenerative diseases, including Huntington’s Disease (HD). Emerging evidence suggests that circadian decline feeds into neurodegenerative symptoms, exacerbating them. ...

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The concept of ‘time’ has been of profound interest and a topic of debate, with deep roots in religion and philosophy, from ancient times to the present day. Some philosophers have even dismissed time as being a mental ...

For centuries, it has been observed that behavioral and physiological processes of most organisms occur in a rhythmic manner with different periodicities (see Daan, 2010). Trees flower and fruit at species-specific seasons ...

The ancient Egyptians were the first known people to use the word 'Brain' when they mentioned about some of the “head-related” illnesses in the papyrus scriptures. Strangely, they used to believe that the heart is the ...

In fruit flies Drosophila melanogaster, environmental cycles of light and temperature are known to influence behavioral rhythms through dedicated sensory receptors. But the thermosensory pathways and molecular receptors ...

We utilized an NMR-based metabolomic approach to profile the metabolites in Drosophila melanogaster that cycle with a daily rhythm. H-1 1D and 2D NMR experiments were performed on whole-body extracts sampled from flies ...