A Surprising Role for the Sch9 Protein Kinase in Chromosome Segregation in Candida albicans

Varshney, Neha; Schaekel, Alida; Singha, Rima; Chakraborty, Tanmoy; van Wijlick, Lasse; Ernst, Joachim F.; Sanyal, Kaustuv

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dc.contributor.author	Varshney, Neha
dc.contributor.author	Schaekel, Alida
dc.contributor.author	Singha, Rima
dc.contributor.author	Chakraborty, Tanmoy
dc.contributor.author	van Wijlick, Lasse
dc.contributor.author	Ernst, Joachim F.
dc.contributor.author	Sanyal, Kaustuv
dc.date.accessioned	2017-01-04T09:05:40Z
dc.date.available	2017-01-04T09:05:40Z
dc.date.issued	2015
dc.identifier.citation	Genetics	en_US
dc.identifier.citation	199	en_US
dc.identifier.citation	3	en_US
dc.identifier.citation	Varshney, N.; Schaekel, A.; Singha, R.; Chakraborty, T.; van Wijlick, L.; Ernst, J. F.; Sanyal, K., A Surprising Role for the Sch9 Protein Kinase in Chromosome Segregation in Candida albicans. Genetics 2015, 199 (3), 671-+.	en_US
dc.identifier.issn	0016-6731
dc.identifier.uri	https://libjncir.jncasr.ac.in/xmlui/10572/1992
dc.description	Restricted access	en_US
dc.description.abstract	The AGC kinase Sch9 regulates filamentation in Candida albicans. Here, we show that Sch9 binding is most enriched at the centromeres in C. albicans, but not in Saccharomyces cerevisiae. Deletion of CaSch9 leads to a 150- to 750-fold increase in chromosome loss. Thus, we report a previously unknown role of Sch9 in chromosome segregation.	en_US
dc.description.uri	1943-2631	en_US
dc.description.uri	http://dx.doi.org/10.1534/genetics.114.173542	en_US
dc.language.iso	English	en_US
dc.publisher	Genetics Society of America	en_US
dc.rights	?Genetics Society of America, 2015	en_US
dc.subject	Genetics & Heredity	en_US
dc.subject	kinase	en_US
dc.subject	Sch9	en_US
dc.subject	centromere	en_US
dc.subject	chromosome segregation	en_US
dc.subject	kinetochore	en_US
dc.subject	Yeast Saccharomyces-Cerevisiae	en_US
dc.subject	Kinetochore	en_US
dc.subject	Gene	en_US
dc.subject	Efficient	en_US
dc.subject	Transmission	en_US
dc.subject	Centromeres	en_US
dc.subject	Longevity	en_US
dc.subject	Chromatin	en_US
dc.subject	Homolog	en_US
dc.subject	MCM21	en_US
dc.title	A Surprising Role for the Sch9 Protein Kinase in Chromosome Segregation in Candida albicans	en_US
dc.type	Article	en_US