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Browsing Nagaraja, V. by Author "Bhowmick, Tuhin"

Browsing Nagaraja, V. by Author "Bhowmick, Tuhin"

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  • Allosteric Transition Induced by Mg2+ Ion in a Transactivator Monitored by SERS 
    Kundu, Partha P.; Bhowmick, Tuhin; Swapna, Ganduri; Kumar, G. V. Pavan; Nagaraja, V.; Narayana, Chandrabhas (American Chemical Society, 2014)
    We demonstrate the utility of the surface-enhanced Raman spectroscopy (SERS) to monitor conformational transitions in protein upon ligand binding. The changes in protein's secondary and tertiary structures were monitored ...
  • Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors 
    Bhowmick, Tuhin; Ghosh, Soumitra; Dixit, Karuna; Ganesan, Varsha; Ramagopal, Udupi A.; Dey, Debayan; Sarma, Siddhartha P.; Ramakumar, Suryanarayanarao; Nagaraja, V. (Nature Publishing Group, 2014)
    The nucleoid-associated protein HU plays an important role in maintenance of chromosomal architecture and in global regulation of DNA transactions in bacteria. Although HU is essential for growth in Mycobacterium tuberculosis ...

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