Kumar, Rupesh; Madhumathi, Bhavani Shankar; Nagaraja, V.
(American Society Microbiology, 2014)
DNA gyrase is a type II topoisomerase that catalyzes the introduction of negative supercoils in the genomes of eubacteria. Fluoroquinolones (FQs), successful as drugs clinically, target the enzyme to trap the gyrase-DNA ...