dc.contributor.author |
Pandeeswar, M.
|
|
dc.contributor.author |
Senanayak, Satyaprasad P.
|
|
dc.contributor.author |
Govindaraju, T.
|
|
dc.date.accessioned |
2017-01-24T06:35:04Z |
|
dc.date.available |
2017-01-24T06:35:04Z |
|
dc.date.issued |
2016 |
|
dc.identifier.citation |
Pandeeswar, M.; Senanayak, S. P.; Govindaraju, T., Nanoarchitectonics of Small Molecule and DNA for Ultrasensitive Detection of Mercury. Acs Applied Materials & Interfaces 2016, 8 (44), 30362-30371 http://dx.doi.org/10.1021/acsami.6b10527 |
en_US |
dc.identifier.citation |
ACS Applied Materials & Interfaces |
en_US |
dc.identifier.citation |
8 |
en_US |
dc.identifier.citation |
44 |
en_US |
dc.identifier.issn |
1944-8244 |
|
dc.identifier.uri |
https://libjncir.jncasr.ac.in/xmlui/10572/2198 |
|
dc.description |
Open Access (Manuscript) |
en_US |
dc.description.abstract |
Reliable and ultrasensitive detection of mercury ions is of paramount importance for toxicology assessment, environmental protection, and human health. Herein, we present a novel optoelectronic approach based on nano architectonics of small-molecule templated DNA system that consists of an adenine (A)-conjugated small organic semiconductor (BNA) and deoxyribo-oligothymidine (dT(n)). This mutually templated dynamic chiral coassembly system (BNAn-dT(n)) with tunable chiroptical, morphological, and electrical properties is tapped in to enable ultrasensitive and selective detection of inorganic and organometallic mercury in water. We observe a rapid transformation of the BNA(n)-dT(n) coassembly into a metallo-DNA duplex [dT-Hg-dT](n), in the presence of mercury, which is utilized for a chiro-optical and conductivity-based rapid and subnanomolar sensitivity (>= 0.1 nM, 0.02 ppb) to mercury ions in water (similar to 100 times lower than United States Environmental Protection Agency tolerance limit). This ultrasensitive detection of inorganic and organometallic mercury is driven by a novel chemical design principle that allows strong mercury thymine interaction. This study is anticipated to inspire the development of future templated DNA nanotechnology-based optoelectronic devices for the rapid and ultrasensitive detection of numerous other toxic analytes. |
en_US |
dc.description.uri |
http://dx.doi.org/10.1021/acsami.6b10527 |
en_US |
dc.language.iso |
English |
en_US |
dc.publisher |
American Chemical Society |
en_US |
dc.rights |
@American Chemical Society, 2016 |
en_US |
dc.subject |
Materials Science |
en_US |
dc.subject |
environmental pollutant |
en_US |
dc.subject |
ultra sensitive detection of mercury |
en_US |
dc.subject |
small organic semiconductor-DNA nanoarchitectonics |
en_US |
dc.subject |
chiroptical and electrical detection |
en_US |
dc.subject |
Functionalized Gold Nanoparticles |
en_US |
dc.subject |
Colorimetric Detection |
en_US |
dc.subject |
Selective Recognition |
en_US |
dc.subject |
Room-Temperature |
en_US |
dc.subject |
Aqueous-Media |
en_US |
dc.subject |
One-Step |
en_US |
dc.subject |
Hg Ii |
en_US |
dc.subject |
Ions |
en_US |
dc.subject |
Water |
en_US |
dc.subject |
Fluorescence |
en_US |
dc.title |
Nanoarchitectonics of Small Molecule and DNA for Ultrasensitive Detection of Mercury |
en_US |
dc.type |
Article |
en_US |