Abstract:
In supramolecular chemistry, the control of helicity is an attractive challenge.It is an
important step towards understanding biological homochirality and function.It can also be
utilized for possible development of novel chiral functional materials that could be used in the
synthesis, sensing and separation of enantiomers. One of the recent design strategies to
construct supramolecular helical polymers is by the use of achiral monomers and chiral
auxiliaries. In this strategy, generally the achiral monomers are functionalized with specific
receptor motifs, to bind with chiral auxiliary (guest) molecules. Further, the achiral monomers
can exist in their monomeric state or in racemic stacks form, which on binding with the chiral
guest molecules will transform into homochiralsupramolecular assemblies. This chapter will
summarize various chiral auxiliary design strategies reported in literature for the construction of
helical supramolecular polymer.
