"Studies of hematopoiesis serve as a paradigm for understanding stem cell properties. Stem cells, by definition, are unspecialized cells with the remarkable potential to self-renew as well as give rise to differentiated ...

"Discovery of the double helical DNA structure in 1953 is considered as one of the most significant landmark events in the field of biology [1]. After this illuminating discovery, the subsequent years saw the continuous ...

"The retroviruses represent a diverse family of RNA containing viruses. In this family of viruses, the RNA is reverse transcribed into double-stranded DNA which subsequently integrates into the genome of the host cell ...

"This chapter is a survey of the available literature on 6-oxopurine phosphoribosyltransferases that includes structural and functional features, conformational changes involved in the process of catalysis, chemical ...

"The eukaryotic genome is systematically packaged into a topologically complex, fibrous superstructure known as chromatin in order to accommodate within the nucleus of the cell. The most basic repeating unit of chromatin ...

Spermatogenesis is a male germ cell differentiation process in which a diploid spermatogonial cell differentiates into mature motile haploid spermatozoa through a series of biochemical and morphological changes. Spermatogenesis ...

Approximately 30 million years ago in the Palaeogene period, first fossil evidence of malaria parasites in the mosquitoes preserved in Dominican amber was found (Figure1.1) (Poinar, 2005). Malaria parasites have diverse ...

"The current study focuses on the preliminary characterisation of a purine nucleotide cycle enzyme, AMP deaminase (AMPD hereafter) from Plasmodium falciparum. Purine nucleotide cycle performs inter-conversion of IMP and ...

"Epilepsy is a chronic and non-communicable disorder of the brain. It is not a single disorder but a group of about 40 different neurological conditions. The most common type of epilepsy in adults is temporal lobe epilepsy ...

"The history of malaria can be traced with the history of mankind. In the Sushruta, a Sanskrit medical treatise (6th century BCE), the symptoms of malarial fever were described and attributed to the bites of certain ...