Browsing Student Theses (MBGU) by Issue Date

Now showing items 1-20 of 168

Cloning and characterization of the eukaryotic initiation factor 2 alpha (eIF 2a) from the malarial parasite plasmodium falciparum

Gurpur, Praveen Bhat (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2001)

Abstract not available
Investigations on the plasmodium falciparum, human and chimeric hypoxanthine guanine phosphoribosyltransferases

Subbayya, Sujay I.N. (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2002)

Abstract not available
Protein structure and dynamics: Studies on the plasmodial proteins - triosephosphate isomerase (TIM) and hypoxanthine guanine phosphoribosyltransferase (HGPRT) and plasmepsin II

Pattaniak, Priyaranjan (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2003)

Abstract not available
Regulation of p53 function by nonhistone chromosomal proteins, HMGB-1 and PC4

Bannerjee, Sourav (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2003)

Abstract not available
Engineering and evaluation of molecular adjuvants for DNA immunogens based on the HIV transactivator (Tat) proteins from Indian isolates

Ramkrishna, Lakshmi (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2003)

HIV infections have reached alarming proportions worldwide. UNAIDS estimated that up to 42 million people were living with HIV/AIDS at the end of 2002. In India, NACO figures suggest that up to 4 million people are ...
Structure-function studies on successive purine salvage pathway enzymes- hypoxanthine guanine phosphoribosyltransferase and adenylosuccinate synthetase

Jayalakshmi, R. (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2004)

Abstract not available
Characterization of asrij expression, function and regulation in embryonic stem cells and the developing cardiovascular system

Mukhopadhyay, Arpita (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2005)

This thesis analyses the expression, function and regulation of a novel gene, asrij. The early expression of Asrij allows its use as an embryonic stem- cell marker that is down-regulated in nonvascular tissues. Asrij ...
Studies on plasmodium falciparum enoyl-ACP reductase (Fabl)

Dar, Mohd Jamal (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2005)

Inhibition of type-II fatty acid biosynthesis has recently been vahdated as an appropriate target for the development of newer antimalarials. The enzyme target of most of the known FAS-II antimicrobial compounds is ...
Regulation of acetylation-dependent chromatin transcription by human nucleophosmin, a histone chaperone

Swaminathan, Venkatesh (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2005)

Abstract not available
Studies on molecular genetic aspects of idiopathic generalized epilepsies

Kapoor, Ashish (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2006)

Epilepsy is a group of chronic neurological conditions characterized by usually unprovoked, recurrent epileptic seizures. Seizures represent the clinical manifestations resulting from abnormal, excessive and hypersynchronous ...
Molecular genetic aspects of non-syndromic hearing loss in India

Ram Shankar, M. (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2006)

In the last decade or so, advances in the areas of human genetics and cell biology have provided a major insight into the molecular mechanisms involved in the development, function and dysfunction of the auditory system. ...
Functional mechanisms of human transcriptional coactivator PC4, a bona fide nonhistone component of chromatin

Das, Chandrima (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2006)

The Eukaryotic genome is organized into a highly complex nucleoprotein structure, chromatin, which is composed of DNA, wrapped around a core histone octamer and a diverse group of nonhistone proteins involved in maintaining ...
Macromolecular uptake In drosophila pericardial cells requires rudhira function

Das, Debjani (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2007)

This thesis reports the molecular-genetic and functional characterization of pericardial cells of Drosophila melanogaster. We describe pericardial cells in terms of their number and gene expression in post-embryonic ...
Rudihira- a novel WD40 protein expressed in embryonic stem cells, erythropoiesis, angiogenesis and tumors

Siva, Kavitha (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2007)

All multi-cellular life begins as a single cell that undergoes several rounds of division followed by differentiation to distinct cell types that make up the tissues and developing organs. Embryos that have only a few ...
Isolation and biological characterization of infectious molecular clones of HIV-1 subtype-C with expanded coreceptor usage from an Indian demented subject

Dash, Prasanta Kumar (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2007)

Twenty five years following its discovery, Human Immunodeficiency Virus (HIV) - the causative agent of Acquired Immuno Deficiency Syndrome (AIDS), still remains a major threat to human beings. The most widely recognized ...
Functional cooperativity of tumor suppressor p53 and transcriptional coactivator PC4: transcription to repair

Batta, Kiran (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2007)

In a complex but highly coordinated eukaryotic system, transcriptional regulation and the regulation of cellular protein functions by covalent modifications are critically important to maintain the cellular homeostasis. ...
Biochemical and molecular insights into β–ketoacyl-Acyl carrier protein reductase (FabG) from plasmodium falciparum

Karmodiya, Krishanpal (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2008)

Man and malaria seem to have evolved together. The origin of malaria parasites can be traced along with the history of mankind. Malaria parasites probably originated in Africa and fossils mosquitoes have been found up ...
Structural and functional characterization of adenylosuccinate synthetase from a mesophilic parasitic protozoan, plasmodium falciparum and a thermophilic archaea methanocaldococcus jannaschii

Mehrotra, Sonali (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2008)

This chapter provides an introduction to the enzyme adenylosuccinate synthetase which forms the theme of the studies reported in this thesis. This is followed by a general description of the life style of the two ...
Optimization of DNA vaccines: molecular strategies to augment immune responses to HIV-1 Tat

K., Anand Kumar (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2008-02-21)

It has been twenty five years since Human Immunodeficiency Virus (HIV) has been identified as the causative agent for Acquired Immunodeficiency Syndrome (AIDS). The pandemic of HIV infection is clearly the defining medical ...
Molecular mechanisms of inhibition of histone acetyltransferases: Implications in antineoplastic therapy

Arif (Jawaharlal Nehru Centre for Advanced Scientific ResearchMolecular Biology and Genetics Unit (MBGU), 2009)

Abstract not available

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