Inhibition of type-II fatty acid biosynthesis has recently been vahdated as an appropriate target for the development of newer antimalarials. The enzyme target of most of the known FAS-II antimicrobial compounds is ...

This thesis analyses the expression, function and regulation of a novel gene, asrij. The early expression of Asrij allows its use as an embryonic stem- cell marker that is down-regulated in nonvascular tissues. Asrij ...

Epilepsy is a group of chronic neurological conditions characterized by usually unprovoked, recurrent epileptic seizures. Seizures represent the clinical manifestations resulting from abnormal, excessive and hypersynchronous ...

Abstract not available

Spermatogenesis is a process in which spermatogonial stem cells undergo a series of biochemical and morphological changes resulting in the production of highly differentiated haploid cells called spermatozoa. The entire ...

This chapter gives an introduction on Plasmodium falciparum life cycle and its metabolism. Studying P. falciparum metabolism will not only lead to novel biochemical targets for chemotherapeutic intervention but also ...

The mechanism of hearing is a complex biological process. In humans, a number of genes are known to underlie this process. Understanding of these genes in auditory physiology is providing substantial information regarding ...

Chromatin is the complex nucleoprotein structure of DNA wrapped around the histones. This structure undergoes several hierarchical and distinct organizational states, aided by not only histones, but also nonhistone ...

The information required for the sustenance of life is encoded in the form of DNA in most organisms except certain viruses where RNA is the genetic material. This information stored in the DNA is decoded in the form of ...

The entire genetic information in a eukaryotic cell is stored in DNA over two meters (approximately) in length. It is compacted to nearly one hundred thousandth of the dimension at different levels of folding with an ...