Browsing Govindaraju, T. by Subject "A-Beta"

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Function and toxicity of amyloid beta and recent therapeutic interventions targeting amyloid beta in Alzheimer's disease

Rajasekhar, K.; Chakrabarti, Malabika; Govindaraju, T. (Royal Society of Chemistry, 2015)

Amyloidogenesis has been implicated in a broad spectrum of diseases in which amyloid protein is invariably misfolded and deposited in cells and organs. Alzheimer's disease is one of the most devastating ailments among ...
A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid beta Aggregates

Rajasekhar, K.; Narayanaswamy, Nagarjun; Murugan, N. Arul; Kuang, Guanglin; Agren, Hans; Govindaraju, T. (Nature Publishing Group, 2016)

A major challenge in the Alzheimer's disease (AD) is its timely diagnosis. Amyloid beta (A beta) aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here, we demonstrate hemicyanine-based ...
Natural Tripeptide-Based Inhibitor of Multifaceted Amyloid beta Toxicity

Rajasekhar, K.; Madhu, Chilakapati; Govindaraju, T. (American Chemical Society, 2016)

Accumulation of amyloid beta (A beta) peptide and its aggregates in the human brain is considered as one of the hallmarks of Alzheimer's disease (AD). The polymorphic oligomers and fully grown fibrilar aggregates of A beta ...

Now showing items 1-3 of 3

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