Research Papers (Jayanta Haldar): Recent submissions

Now showing items 21-23 of 23

Lipophilic vancomycin aglycon dimer with high activity against vancomycin-resistant bacteria

Yarlagadda, Venkateswarlu; Sarkar, Paramita; Manjunath, Goutham B.; Haldar, Jayanta (Pergamon-Elsevier Science Ltd, 2015)

Antibiotic-resistant superbugs such as vancomycin-resistant Enterococci (VRE) and Staphylococci have become a major global health hazard. To address this issue, we synthesized vancomycin aglycon dimers to systematically ...
Tackling vancomycin-resistant bacteria with 'lipophilic-vancomycin-carbohydrate conjugates'

Yarlagadda, Venkateswarlu; Konai, Mohini M.; Manjunath, Goutham B.; Ghosh, Chandradhish; Haldar, Jayanta (Japan Antibiotics Research Association, 2015)

Vancomycin, a glycopeptide antibiotic, has long been a drug of choice for life-threatening Gram-positive bacterial infections. Vancomycin confers its antibacterial activity by inhibiting bacterial cell wall biosynthesis. ...
Membrane Active Small Molecules Show Selective Broad Spectrum Antibacterial Activity with No Detectable Resistance and Eradicate Biofilms

Hoque, Jiaul; Konai, Mohini M.; Gonuguntla, Spandhana; Manjunath, Goutham B.; Samaddar, Sandip; Yarlagadda, Venkateswarlu; Haldar, Jayanta (American Chemical Society, 2015)

Treating bacterial biofilms With conventional antibiotics is limited due to ineffectiveness of the drugs and higher propensity to develop bacterial resistance. Development of new classes of antibacterial therapeutics with ...

Now showing items 21-23 of 23

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