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Browsing Faculty publications (MBGU) by Issue Date

Browsing Faculty publications (MBGU) by Issue Date

Now showing items 1-20 of 189

δ-Aminolaevulate Synthetase Induction and Catalase Repression by Porphyrinogenic Drugs

Rao, M R S; Padmanaban, G (The Biochemical Society (Portland Press), 1971)
Effect of Hexachlorobenzene on Haem Synthesis

Rajamanickam, Chellam; Amrutavalli, J; Rao, M R S; Padmanaban, G (The Biochemical Society (Portland Press), 1972)

Several drugs are known to induce the liver microsomal mixed-function oxidase system when administered in vivo or even in vitro in cell culture. A sequence of events has been suggested in which the drug is visualized to ...
The Relationship between Delta-Aminolaevulinate Synthetase Induction and the Concentrations of Cytochrome P-450 and Catalase in Rat Liver

Rao, M R S; Malathi, K; Padmanaban, G (The Biochemical Society, 1972)

The porphyrinogenic drug 2-allyl-2-isopropylacetamide causes the degradation of microsomal cytochrome P-450 and inhibits the synthesis of catalase in rat liver. The inhibition of catalase synthesis follows the induction ...
Biochemical Effects of the Porphyrinogenic Drug Allyisopropylacetamide

Rao, M R S; Padmanaban, Govindarajan (Portland Press, 1973)

Successive administrations of allylisopropylacetamide, a potent porphyrinogenic drug, increase liver weight, microsomal protein and phospholipid contents. There is an increase in the rate of microsomal protein synthesis ...
A Model for the Regulation of delta-Aminolaevulinate Synthetase Induction in Rat Liver

Padmanaban, Govindarajan; Rao, M R S; Malathi, Krishnamachari (The Biochemical Society, 1973-08)

A reciprocal relationship exists between the cytochrome P-450 content and δ-aminolaevulinate synthetase activity in adult rats. In young rats the basal δ-aminolaevulinate synthetase activity is higher and the cytochrome ...
On the Sequence of Reactions Leading to Cytochrome P-450 Synthesis-Effect of Drugs

Rajamanickam, Chellam; Rao, M R S; Padmanaban, Govindarajan (The American Society for Biochemistry and Molecular Biology Inc, 1975)

The effect of phenobarbital on the rates of the synthesis of the protein and heme moieties of cytochrome P-450 has been studied. For this purpose, cytochrome P-450 has been partially purified as its P-420 derivative and ...
Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver

Sardana, M K; Rao, M R S; Padmanaban, G (Portland Press, 1975)

The porphyrogenic drug allylisopropylacetamide, a potent inducer of delta-aminolaevulinate synthetase, specifically increases nucleoplasmic RNA synthesis in rat liver. The drug-mediated increase in nucleoplasmic RNA synthesis ...
Antigenically active nonhistone chromatin proteins in cancer cells

Busch, Harris; Yeoman, Lynn C; Busch, Rose K; Jordan, John J; Rao, M R S; Taylor, Charles W; Wu, Benjamin C (American Association for Cancer Research, 1976-09)

Two-dimensional polyacrylamide gel electrophoresis shows that in nuclei of Novikoff hepatoma ascites cells there are approximately 75 proteins in the chromatin fraction soluble in 3 m NaCl:7 m urea. Dialysis of this fraction ...
Effects of U1 Nuclear RNA on Translation of Messenger RNA

Rao, M R S; Blackstone, Marilyn; Busch, Harris (American Chemical Society, 1977-06)

U 1 nuclear RNA has the 5’-terminal sequence m32,2,7Gpp(p)AmUmACUUACCUGGCAGGGAGAUACCAGG- [Reddy, R., et al. (1974), J. Biol. Chem. 249, 6486; Ro-Choi, T. S., et al. (l974), Fed. Proc., Fed. Am. Soc. Exp. Biol. 33, ...
Isolation and Characterization of Binding Proteins for Retinol from the Cytosol, Nucleosol and Chromatin of the Oviduct Magnum of Laying Hens

Rao, M R S; Prasad, V R; Padmanaban, Govindarajan; Ganguly, Jagannath (The Biochemical Society, 1979)

Protein fractions that bind retinol were isolated from the cytosol, nucleosol and chromatin of the oviduct magnum of laying hens. The proteins isolated from the three sources showed similar elution profiles on chromatography ...
A Comparative Study of the Early Effects of Phenobarbital and 3-Methylcholanthrene on the Synthesis and Transport of Ribonucleic Acid in Rat Liver

Kumar, Ashwani; Rao, M R S; Padmanaban, Govindarajan (The Biochemical Society, 1980)

At 2-3 h after phenobaribtal administration, the drug has no effect on nucleoplasmic RNA synthesis and decreases nucleolar RNA synthesis. However, at this time there is an increase in the labelling of cytoplasmic ...
Localization of testis-variant histones in rat testis chromatin

Rao, M R S; Rao, Basuthkar Jagadeeshwar; Ganguly, Jagannath (The Biochemical Society, 1982)

Nucleosome core particles and oligonucleosomes were isolated by digesting rat testis nuclei with micrococcal nuclease to 20% acid-solubility, followed by fractionation of the digest on a Bio-Gel A-5m column. The core ...
Structural organization of the meiotic prophase chromatin in rat testes

Rao, Basuthkar Jagadeeswar; Brahmachari, Samir K; Rao, M R S (American Society for Biochemistry and Molecular Biology, 1983)

Pachytene nuclei were isolated from rat testes by the unit gravity sedimentation technique and contained histone variants H1a, H1t, TH2A, TH2B, and X2 in addition to the somatic histones H1bde, H1c, H2A, H2B, H3, and H4. ...
A quantitative analysis of germ cells and the histone variants in the testes of vitamin A-deficient rats and during subsequent repletion with vitamin A

Unni, Emmanual; Rao, M R S (Indian Academy of Sciences, 1985-06)

A quantitative analysis of the different types of germ cells present in the seminiferous tubules of vitamin A-deficient-retinoate maintained rats revealed that the number of pachytene spermatocytes and spermatogonia was ...
Testis-specific Histone H1 t Is Antigenically Distinct among H1 Subtypes

Markose, Elizabeth R; Rao, M R S (The American Society for Biochemistry and Molecular Biology Inc, 1985-12-25)

Histone Hlt has been purified from rat testes and antibodies were elicited in rabbits. Immunoblotting studies with anti-histone Hlt-IgG have shown that it reacted specifically with histone Hlt but not with other histone ...
Identification of a Meiotic Prophase-specific Nuclear Matrix Protein in the Rat

Behal, Amita; Prakash, Kulkarni; Rao, M R S (The American Society for Biochemistry and Molecular Biology Inc, 1987)

We have identified a 110-kDa pI 5.6 phosphoprotein with DNA binding properties in the rat pachytene spermatocyte nuclear matrix. By immunoblotting and indirect immunofluorescence assays using polyclonal antibodies against ...
Interaction of rat testis protein, TP, with nucleic acids in vitro. Fluorescence quenching, UV absorption, and thermal denaturation studies

Singh, Jagmohan; Rao, M R S (The American Society for Biochemistry and Molecular Biology Inc, 1987)

The nucleic acid binding properties of the testis protein, TP, were studied with the help of physical techniques, namely, fluorescence quenching, UV difference absorption spectroscopy, and thermal melting. Results of ...
DNase I Site Mapping and Micrococcal Nuclease Digestion of Pachytene Chromatin Reveal Novel Structural Feature

Rao, Jagadeeshwar B; Rao, M R S (American Society for Biochemistry and Molecular Biology Inc, 1987-04-05)

A comparison of the DNase I digestion products of the 32P-5’-end-labeled pachytene nucleosome core particles (containing histones H2A, TH2A, X2, H2B, THPB, H3a, nd H4) and liver nucleosome core particles (containing somatic ...
Characterization of poly(ADP-ribosyl)ated domains of rat pachytene chromatin

Satyanarayana, Karuturi; Rao, M R S (Portland Press, 1989-08-01)

Poly(ADP-ribosyl)ation of nuclear proteins was several-fold higher in the pachytene spermatocytes than in the premeiotic germ cells of the rat. Among the histones of the pachytene nucleus, histone subtypes H2A, H1 and H3 ...
An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A

Heyer, Wolf-Dietrich; Rao, M R S; Erdile, Lorne F; Kelly, ThomasJ; Kolodner, R D (Oxford University Press, 1990-07)

Single-stranded DNA binding proteins (SSBs) are known to play a role in DNA replication and recombination in prokaryotes. An SSB was previously purified from the yeast Saccharomyces cerevisiae. This SSB stimulated the ...

Now showing items 1-20 of 189

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