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Browsing Tapas Kumar Kundu by Author "Agrawal, Shipra"

Browsing Tapas Kumar Kundu by Author "Agrawal, Shipra"

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  • Biology of Aurora A Kinase: Implications in Cancer Manifestation and Therapy 
    Karthigeyan, Dhanasekaran; Benaka Prasad, Sallekoppal B; Shandilya, Jayasha; Agrawal, Shipra; Kundu, Tapas K (Wiley Blackwell, 2010-03-01)
    The Aurora A kinase belongs to serine/threonine group of kinases, well known for its role in cell cycle, especially in the regulation of mitosis. Numerous substrates of Aurora A kinase have been identified, which are ...
  • Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin 
    Ravindra, Kodihalli C; Selvi, B Ruthrotha; Arif, Mohammed; Reddy, B A Ashok; Thanuja, Gali R; Agrawal, Shipra; Pradhan, Suman Kalyan; Nagashayana, Natesh; Dasgupta, Dipak; Kundu, Tapas K (American Society for Biochemistry and Molecular Biology Inc, 2009-09-04)
    Lysine acetyltransferases (KATs), p300 (KAT3B), and its close homologue CREB-binding protein (KAT3A) are probably the most widely studied KATs with well documented roles in various cellular processes. Hence, the dysfunction ...
  • Mechanism of p300 Specific Histone Acetyltransferase Inhibition by Small Molecules 
    Arif, M; Pradhan, Suman Kalyan; Thanuia, G R; Vedamurthy, B M; Agrawal, Shipra; Dasgupta, Dipak; Kundu, Tapas K (American Chemical Society, 2009-01-22)
    Dysfunction of histone acetyltransferases (HATs) leads to several diseases including cancer, diabetes, and asthma. Therefore, small molecule inhibitors and activators of HATs are being considered as new generation therapeutics. ...
  • Specific Small-Molecule Activator of Aurora Kinase A Induces Autophosphorylation in a Cell-Free System 
    Kishore, A Hari; Vedamurthy, B M; Mantelingu, K; Agrawal, Shipra; Reddy, B A Ashok; Roy, Siddhartha; Rangappa, K S; Kundu, Tapas K (American Chemical Society, 2008-01-24)
    Aurora kinases are essential for chromosomal segregation and cell division and thereby important for maintaining the proper genomic integrity. There are three classes of aurora kinases in humans: A, B, and C. Aurora kinase ...

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