Vasudevarao, Mohankrishna Dalvoy; Mizar, Pushpak; Kumari, Sujata; Mandal, Somnath; Siddhanta, Soumik; Swamy, Mahadeva M. M.; Kaypee, Stephanie; Kodihalli, Ravindra C.; Banerjee, Amrita; Naryana, Chandrabhas; Dasgupta, Dipak; Kundu, Tapas Kumar
(American Society Biochemistry Molecular Biology Inc, 2014)
Background: 1,4-Naphthoquinone analogs, such as plumbagin, are toxic compounds due to their redox cycling and thiol-reactive properties. Results: The p300 inhibitor PTK1, a plumbagin derivative with greatly reduced toxicity, ...