Cyclization and unsaturation rather than isomerisation of side chains govern the selective antibacterial activity of cationic-amphiphilic polymers

Uppu, D. S. S. M.; Bhowmik, M.; Samaddar, S.; Haldar, Jayanta

dc.contributor.author	Uppu, D. S. S. M.
dc.contributor.author	Bhowmik, M.
dc.contributor.author	Samaddar, S.
dc.contributor.author	Haldar, Jayanta
dc.date.accessioned	2017-01-24T09:11:14Z
dc.date.available	2017-01-24T09:11:14Z
dc.date.issued	2016
dc.identifier.citation	Uppu, Dssm; Bhowmik, M.; Samaddar, S.; Haldar, J., Cyclization and unsaturation rather than isomerisation of side chains govern the selective antibacterial activity of cationic-amphiphilic polymers. Chemical Communications 2016, 52 (25), 4644-4647 http://dx.doi.org/10.1039/c5cc09930g	en_US
dc.identifier.citation	Chemical Communications	en_US
dc.identifier.citation	52	en_US
dc.identifier.citation	25	en_US
dc.identifier.issn	1359-7345
dc.identifier.uri	https://libjncir.jncasr.ac.in/xmlui/10572/2307
dc.description	Open Access (Accepted Manuscript); Restricted Access (Publisher's PDF)	en_US
dc.description.abstract	Membrane-active agents represent a promising alternative to overcome antibiotic resistance. Here, we report cationic-amphiphilic polymers with variations in the side chain architecture such as cyclization, isomerization and unsaturation that resulted in potent antibacterial activity and low mammalian cell toxicity with a membrane-active mode of action.	en_US
dc.description.uri	1364-548X	en_US
dc.description.uri	http://dx.doi.org/10.1039/c5cc09930g	en_US
dc.language.iso	English	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.rights	@Royal Society of Chemistry, 2016	en_US
dc.subject	Chemistry	en_US
dc.subject	Antimicrobial Peptides	en_US
dc.subject	Copolymers	en_US
dc.subject	Potent	en_US
dc.subject	Agents	en_US
dc.title	Cyclization and unsaturation rather than isomerisation of side chains govern the selective antibacterial activity of cationic-amphiphilic polymers	en_US
dc.type	Article	en_US