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Research Papers (M.R.S. Rao): Recent submissions

Now showing items 41-60 of 72

A Model for the Regulation of delta-Aminolaevulinate Synthetase Induction in Rat Liver

Padmanaban, Govindarajan; Rao, M R S; Malathi, Krishnamachari (The Biochemical Society, 1973-08)

A reciprocal relationship exists between the cytochrome P-450 content and δ-aminolaevulinate synthetase activity in adult rats. In young rats the basal δ-aminolaevulinate synthetase activity is higher and the cytochrome ...
A quantitative analysis of germ cells and the histone variants in the testes of vitamin A-deficient rats and during subsequent repletion with vitamin A

Unni, Emmanual; Rao, M R S (Indian Academy of Sciences, 1985-06)

A quantitative analysis of the different types of germ cells present in the seminiferous tubules of vitamin A-deficient-retinoate maintained rats revealed that the number of pachytene spermatocytes and spermatogonia was ...
Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma

Somasundaram, Kumaravel; Reddy, Sreekanth P; Vinnakota, Katyayni; Britto, Ramona; Subbarayan, Madhavan; Nambiar, Sandeep; Hebbar, Aparna; Samuel, Cini; Shetty, Mitesh; Sreepathi, Hari Kishore; Santosh, Vani; Hegde, Alangar Sathyaranjandas; Hegde, Sridevi; Kondaiah, Paturu; Rao, M R S (Nature Publishing Group, 2005-10-27)

Astrocytoma is the most common type of brain cancer constituting more than half of all brain tumors. With an aim to identify markers describing astrocytoma progression, we have carried out microarray analysis of astrocytoma ...
Identification of a 34 Amino Acid Stretch within the C-Terminus of Histone H1 As the DNA-Condensing Domain by Site-Directed Mutagenesis

Bharath, M M Srinivas; Ramesh, Sneha; Chandra, Nagasuma R; Rao, M R S (American Chemical Society, 2002-06-18)

The C-terminus of histone HI is necessary for the folding of polynucleosomal arrays into higher-order structure(s) and contains octapeptide repeats each having DNA binding S/TPKK motifs. These repeat motifs were earlier ...
An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A

Heyer, Wolf-Dietrich; Rao, M R S; Erdile, Lorne F; Kelly, ThomasJ; Kolodner, R D (Oxford University Press, 1990-07)

Single-stranded DNA binding proteins (SSBs) are known to play a role in DNA replication and recombination in prokaryotes. An SSB was previously purified from the yeast Saccharomyces cerevisiae. This SSB stimulated the ...
Effect of polymorphisms in the PPARGC1A gene on body fat in Asian Indians

Vimaleswaran, K S; Radha, V; Anjana, M; Deepa, R; Ghosh, S; Majumder, P P; Rao, M R S; Mohan, V (Nature Publishing Group, 2006-06)

Objective: To evaluate whether polymorphisms in the peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PPARGC1A) gene were related to body fat in Asian Indians. Methods: Three polymorphisms of PPARGC1A ...
Stage-Dependent Changes In Localization Of A Germ Cell-Specific Lamin During Mammalian Spermatogenesis

Sudhakar, L; Rao, M R S (American Society for Biochemistry and Molecular Biology Inc, 1990-12-25)

We had earlier identified a 110/120-kDa protein specific to nuclear matrix of rat pachytene spermatocytes (Behal, A., Prakash, K., and Rao, M. R. S. (1987) J. Biol. Chem. 262, 10898-10902). This protein is now shown to be ...
Molecular modeling of the chromatosome particle

Bharath, M M S; Chandra, Nagasuma R; Rao, M R S (Oxford University Press, 2003-07-15)

In an effort to understand the role of the linker histone in chromatin folding, its structure and location in the nucleosome has been studied by molecular modeling methods. The structure of the globular domain of the rat ...
A novel association of a polymorphism in the Wrst intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians

Vimaleswaran, Karani S; Radha, Venkatesan; Ramya, Kandaswamy; Babu, Hunsur Narayan Sathish; Savitha, Nageshappa; Roopa, Venkataramaiah; Monalisa, Dhar; Deepa, Raj; Ghosh, Saurabh; Majumder, Partha P; Rao, M R S; Mohan, Viswanathan (Springer, 2008-07)

Adiponectin is an adipose tissue specific protein that is decreased in subjects with obesity and type 2 diabetes. The objective of the present study was to examine whether variants in the regulatory regions of the adiponectin ...
HUMHOT: a database of human meiotic recombination hot spots

Nishant, K T; Kumar, Chetan; Rao, M R S (Oxford University Press, 2006-01-01)

Meiotic recombination occurs preferentially at certain regions in the genome referred to as hot spots. The number of hot spots known in humans has increased manifold in recent years. The identification of these hot spots ...
Zinc Dependent Recognition of a Human CpG Island Sequence by the Mammalian Spermatidal Protein TP2

Kundu, Tapas K; Rao, M R S (American Chemical Society, 1996-12-10)

Rat spermatidal protein TP2 is a zinc metalloprotein with two atoms of zinc coordinated to cysteine and histidine residues and condenses alternating GC copolymer preferentially in a zinc dependent manner [Kundu, T. K., & ...
Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India

Ramprasad, S; Radha, V; Mathias, R A; Majumder, P P; Rao, M R S; Rema, M (Nature Publishing Group, 2007-03)

Purpose The main objective of this study was to evaluate if the -429T/C, -374T/A and 63 bp deletion polymorphisms in the RAGE gene are associated with diabetic retinopathy (DR) among Type 2 diabetic subjects in a clinic-based ...
Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects

Radha, V; Vimaleswaran, Karani S; Babu, H N S; Abate, Nicola; Chandalia, Manisha; Satija, Pankaj; Grundy, Scott M; Ghosh, Saurabh; Majumder, Partha P; Deepa, Raj; Rao, M R S; Mohan, Viswanathan (American Diabetes Association, 2006-05)

OBJECTIVE - To determine whether the peroxisome proliferator-activated receptor (PPAR)-gamma Pro12ala polymorphism modulates susceptibility to diabetes in South Asians. RESEARCH DESIGN AND METHODS - South Asians (n = ...
A Novel Structure-Specific Endonuclease Activity Associated with Polypyrimidine-Tract Binding (PTB) Related Protein from Rat Testis

Haldar, Devyani; Acharya, Samir; Rao, M R S (American Chemical Society, 2002-10-01)

Nucleases are involved in the processing of various intermediates generated during crucial DNA metabolic processes such as replication, repair, and recombination and also during maturation of RNA precursors. An endonuclease, ...
On the Sequence of Reactions Leading to Cytochrome P-450 Synthesis-Effect of Drugs

Rajamanickam, Chellam; Rao, M R S; Padmanaban, Govindarajan (The American Society for Biochemistry and Molecular Biology Inc, 1975)

The effect of phenobarbital on the rates of the synthesis of the protein and heme moieties of cytochrome P-450 has been studied. For this purpose, cytochrome P-450 has been partially purified as its P-420 derivative and ...
CREMOFAC—a database of chromatin remodeling factors

Shipra, Agrawal; Chetan, Kumar; Rao, M R S (Oxford University Press, 2006-12-01)

Motivation: Chromatin-remodeling is an important event in the eukaryotic nucleus rendering nucleosomal DNA accessible for various transaction processes. Remodeling Factors facilitate the dynamic nature of chromatin through ...
Testis-specific Histone H1 t Is Antigenically Distinct among H1 Subtypes

Markose, Elizabeth R; Rao, M R S (The American Society for Biochemistry and Molecular Biology Inc, 1985-12-25)

Histone Hlt has been purified from rat testes and antibodies were elicited in rabbits. Immunoblotting studies with anti-histone Hlt-IgG have shown that it reacted specifically with histone Hlt but not with other histone ...
Characterization of a mouse recombination hotspot locus encoding a novel non-protein coding RNA

Nishant, K T; Ravishankar, H; Rao, M R S (American Society for Microbiology, 2004-06)

Our current knowledge of recombination hot spot activity in mammalian systems implicates a role for both the primary DNA sequence and the nature of the chromatin domain around it. In mice, the only recombination hot spots ...
Spatiotemporal Organization of AT- and GC-rich DNA and Their Association With Transition Proteins TP1 and TP2 in Rat Condensing Spermatids

Kolthur-Seetharam, Ullas; Pradeepa, Madapura M; Gupta, Nikhil; Narayanaswamy, Rammohan; Rao, M R S (Sage Publications Ltd, 2009-10)

Transition protein 1 (TP1) and TP2 replace histones during midspermiogenesis (stages 12-15) and are finally replaced by protamines. TPs play a predominant role in DNA condensation and chromatin remodeling during mammalian ...
Interaction Of Spermatid-Specific Protein-Tp2 With Nucleic-Acids, Invitro - A Comparative-Study With Tp1

Baskaran, Rajasekaran; Rao, M R S (American Society for Biochemistry and Molecular Biology Inc, 1990-12-05)

TP2 was purified from rat testes employing a gentle method involving differential salt extraction of the sonication-resistant spermatid nuclei. The nucleic acid binding properties of TP2 were studied by fluorescence ...

Now showing items 41-60 of 72

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