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Identification and characterization of the centromere in human pathogenic yeast candida tropicalis

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dc.contributor.advisor Sanyal, Kaustuv
dc.contributor.author Chatterjee, Gautam
dc.date.accessioned 2021-05-18T09:41:06Z
dc.date.available 2021-05-18T09:41:06Z
dc.date.issued 2014
dc.identifier.citation Chatterjee, Gautam. 2014, Identification and characterization of the centromere in human pathogenic yeast candida tropicalis, Ph.D thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru en_US
dc.identifier.uri https://libjncir.jncasr.ac.in/xmlui/handle/123456789/3111
dc.description.abstract "Cell division is one of the most fundamental and conserved processes, by which a mother cell transmits genetic material to its progeny. The sequence of events that help a mother cell to give rise to identical daughter cells is known as the mitotic cell cycle. The mitotic cell cycle involves the two important phases that are temporally separated in eukaryotes. These two phases of the cell cycle are termed as S (synthetic) phase and M (mitotic) phase (Figure 1). The M phase is further sub-divided into four important stages - prophase, metaphase, anaphase and telophase. During prophase, the chromatin fibers (DNA molecules in association with RNA and protein components in a cell) condense into highly compact form to facilitate chromosome segregation. In metaphase, the condensed sister chromatids are bivalently attached to the segregating apparatus, the spindle. Anaphase is initiated by the separation of the duplicated chromatids to the opposite poles. Finally duplicated chromatids segregate from each other at telophase, chromatin again decondenses and cell division is completed by the physical separation of the cytoplasm into two daughter cells by reformation of the nuclear envelope. However, it is noteworthy that these stages are very short in yeasts and are not easily separable." en_US
dc.language.iso English en_US
dc.publisher Jawaharlal Nehru Centre for Advanced Scientific Research en_US
dc.rights © 2014 JNCASR
dc.subject Candida tropicalis en_US
dc.subject Centromere-human pathogenic yeast en_US
dc.title Identification and characterization of the centromere in human pathogenic yeast candida tropicalis en_US
dc.type Thesis en_US
dc.type.qualificationlevel Doctoral en_US
dc.type.qualificationname Ph.D en_US
dc.publisher.department Molecular Biology and Genetics Unit (MBGU) en_US


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