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In our studies we have chosen mutant huntingtin (mHTT) protein as a cargo to study aggrephagy, where an expansion of the polyglutamine (polyQ) tract in its N-terminus leads to aggregation and is a cause of Huntington’s ...

The term ‘meiosis’ originates from the Ancient Greek word meíōsis, which means “a lessening”. This is apt, given that the process of meiosis is a special mode of cell division wherein chromosome number or ploidy is halved, ...

Differentiation from pluripotent cells entails specification of cell intermediates with progressively limited potency. Understanding the molecular mechanisms that specify these intermediates can aid their expansion for ...

Energy metabolism in Plasmodium falciparum asexual stages is unique with respect to the set of pathways used to achieve the objective function of biomass production. ATP demand of the parasite is almost completely met ...

Plasmodium falciparum is one of the five species of Plasmodium that infect humans to cause malaria, which is one of the leading causes of death in low-income countries. It possesses a highlyspecialized metabolism which ...

Autophagy is an evolutionarily conserved intracellular degradation process which maintains cellular homeostasis. This involves the capture and delivery of cytoplasmic contents by the hallmark organelles called autophagosomes ...

LncRNAs have emerged as sentinels in the regulation of various cellular processes and hence, it is not surprising that the number of long non-coding RNA genes correlate with developmental complexity over the course of ...

Abstract not available