In this work, we identified and characterized centromeres and studied their structural organization in a group of Cryptococcus species of the fungal phylum Basidiomycota. Further, we examined the spatio-temporal dynamics ...

This thesis elucidates the molecular and cellular functions of Rudhira in regulating kidney function using Drosophila and mouse models. Drosophila nephrocytes are the structural and functional homolog of the mammalian ...

Cancer is defined as the group of related disease which involves abnormal cell growth with the potential to invade surrounding tissues and other parts of the body. Many cancers form solid tumors which are malignant. There ...

Abstract not available

Abstract not available

Abstract NA

This thesis describes the functional role of BCAS3, a cytoskeletal protein that is essential for blood vessel formation. BCAS3 is the human ortholog of mouse Rudhira, which is expressed during embryonic vascular development ...

Epilepsy is relatively common neurological disorder affecting 1-3% of population during their lifetime (Delgado-Escueta AV et al 2013; Pandolfo M 2013; Thomas HR and Berkovic SF 2014). Epilepsy is characterized by usually ...

Cells maintain homeostasis by a continuous process of synthesis and degradation of their constituent proteins and organelles. This facilitates the cell to remain as a dynamic entity responding rapidly to changing ...

Comparison of genomes of closely related species or different isolates within a species show variations at the DNA sequence level or in their structural organization in a chromosome (BARRACLOUGH et al. 2003). The generation ...