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Characterization and essentiality of the fungal specific dam1 complex in pathogenic yeast candida tropicalis

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dc.contributor.advisor Sanyal, Kaustuv
dc.contributor.author Ram, Sundar S.
dc.date.accessioned 2021-05-17T10:07:31Z
dc.date.available 2021-05-17T10:07:31Z
dc.date.issued 2014
dc.identifier.citation Ram, Sundar S. 2014, Characterization and essentiality of the fungal specific dam1 complex in pathogenic yeast candida tropicalis, MS thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru en_US
dc.identifier.uri https://libjncir.jncasr.ac.in/xmlui/handle/123456789/3103
dc.description.abstract "Mitotic cell cycle ensures that the progeny cell receives a complete complement of the genome from the parent. Whenever growth supportive conditions exist, the cell senses and commits itself to the process of cell division that can be temporally delineated as the G1 (Gap1) phase, S (synthesis) phase, G2 (Gap2) phase and M (mitotic). Checkpoints are placed at G1/S, G2/M and metaphase-anaphase transitions the to ensure that key processes such as DNA replication, repair and chromosome segregation are completed at the desired phase. One of the key processes central to cell division is the segregation of sister chromatids, ensuring the daughter cells receive an equal genetic complement. The process of segregation is not initiated unless all the chromosomes are properly bi-oriented to spindles emanating from spindle pole bodies (SPBs). Premature segregation is avoided by sister chromatid cohesion and also by the spindle assembly checkpoint (SAC) that senses improper/ unattached kinetochore(KT) and arrests the cell cycle prior to anaphase (Lara-Gonzalez et al., 2012). " en_US
dc.language.iso English en_US
dc.publisher Jawaharlal Nehru Centre for Advanced Scientific Research en_US
dc.rights © 2014 JNCASR
dc.subject Candida tropicalis en_US
dc.title Characterization and essentiality of the fungal specific dam1 complex in pathogenic yeast candida tropicalis en_US
dc.type Thesis en_US
dc.type.qualificationlevel Master en_US
dc.type.qualificationname MS en_US
dc.publisher.department Molecular Biology and Genetics Unit (MBGU) en_US


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