dc.contributor.advisor |
Kundu, Tapas Kumar |
|
dc.contributor.author |
Singh, Akash Kumar |
|
dc.date.accessioned |
2021-10-01T06:04:50Z |
|
dc.date.available |
2021-10-01T06:04:50Z |
|
dc.date.issued |
2017 |
|
dc.identifier.citation |
Singh, Akash Kumar. 2017, Role of lysine acetyltransferases p300/CBP in neurological disorders: implications in therapeutics, MS thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru |
en_US |
dc.identifier.uri |
https://libjncir.jncasr.ac.in/xmlui/handle/123456789/3176 |
|
dc.description |
Open access |
en_US |
dc.description.abstract |
1. CSP-TTK21 could be delivered orally to the mice brain.
2. Oral delivery of CSP-TTK21 shows similar activity as IP administration.
3. CSP-TTK21 induces Long term potentiation (LTP) in hippocampal slices without altering the
basal synaptic transmission.
4. CSP-TTK21 could rescue LTP deficits in Syngap1 heterozygous mouse model for Intellectual
Disability (ID). |
en_US |
dc.language |
English |
en |
dc.language.iso |
en |
en_US |
dc.publisher |
Jawaharlal Nehru Centre for Advanced Scientific Research |
en_US |
dc.rights |
JNCASR theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. |
en |
dc.subject |
Neurological disorder |
en_US |
dc.subject |
Medicine |
en_US |
dc.title |
Role of lysine acetyltransferases p300/CBP in neurological disorders: implications in therapeutics |
en_US |
dc.type |
Thesis |
en_US |
dc.type.qualificationlevel |
master |
en_US |
dc.type.qualificationname |
ms |
en_US |
dc.publisher.department |
MBGU |
en_US |